Yes, you can create a wood accent wall with pallet wood for a rustic, reclaimed look. Make sure the pallets are clean, free of harmful chemicals, and in good condition. Sand the wood to smooth rough edges and remove any splinters. You can stain or paint the pallet wood for a finished look or leave it natural for a more rustic appearance. Keep in mind that pallet wood may vary in size and color, so plan your layout carefully to create a balanced design.